PSV's cautious approach in the first half seemed destined for a goalless draw, but Shakhtar struck just before the break. While Sergiño Dest lay injured on the ground, Gleiker Mendoza scored from a distance with a clever shot. The VAR deemed there was no reason to review the decision (0-1).
PSV equalised shortly after the restart through a Sergiño Dest goal, which made up for his earlier mistake. The team, managed by Peter Bosz, responded well to the setback. A similar scenario to last season was not an option, as PSV began the competitive phase of the Champions League with a disappointing home loss against Union Sint-Gillis. Peter Bosz opted for Filip Kostic as a replacement for the suspended Mauro Júnior and deployed Paul Wanner in the position of Noah Fernandez, who had to settle for a place on the bench.
PSV will resume their Champions League campaign next month with an away match against RB Leipzig, a rematch with Johan Bakayoko.