The absence of McTominay is a significant blow for Napoli, who are already struggling with a number of injury concerns. Massimiliano Allegri's side will also be without Italy international centre-back Alessandro Buongiorno, who has been out for the start of the 2026-27 season. Luca Marianucci and Giovane are also out longer term.
According to the latest updates, Allegri has two new injury concerns to contend with ahead of the visit from Arsenal, as neither Andre-Frank Zambo Anguissa nor David Neres participated in training with the rest of the first-team group this morning. This means that both players are now extremely unlikely to be included in the starting line-up to face Arsenal on Wednesday.
The absence of Anguissa is particularly concerning, given that he has started in all three of Napoli's league matches so far this season and is a mainstay in the Partenopei midfield when fit and available. With no McTominay and likely no Anguissa either, Allegri will be increasingly reliant on Stanislav Lobotka in the centre of midfield.
It is also likely that Kevin De Bruyne is brought into the side for his first start of the 2026-27 season against Arsenal on Wednesday. Billy Gilmour and Antonio Vergara are the most likely candidates to complete the midfield three. Napoli's 2026-27 Champions League campaign gets underway with a visit from Arsenal on Wednesday evening.