Amorim got his Serie A career off to a winning start with a 2-1 victory away against Torino last weekend thanks to goals from teenager Alphadjo Cisse and reliable midfielder Adrien Rabiot. Newly-promoted Venezia fell to a 2-0 defeat on home soil against Lecce last time out.
The absence of Rafael Leao, who continues to be linked with a move away in the final week of the summer transfer window, will be a significant blow to Amorim's side. The Portugal international is still being linked with a potential move to either Aston Villa or Galatasaray with just a few days of the summer transfer window remaining.
Pre-match reports from Sky Sport Italia indicate that the Rossoneri are unlikely to make any changes to their winning side, and that Cisse, Goncalo Ramos and Ruben Loftus-Cheek are still expected to lead the attack on Friday evening. Christian Pulisic is unlikely to be included in the starting line-up this evening, but Amorim hinted during his pre-match press conference that he could be in line to earn his first minutes of the season off the substitutes bench.
Kick-off is due at 19.45 BST.