PSV played their last Champions League match against Bayern München in January, which ended in a 1-2 defeat. Mauro Júnior received his second yellow card in the match, resulting in his red card. He was sent off in the match, with Filip Kostic being the most likely replacement. The team will also be without several other players, including Sam Lammers, Sami Ouaissa, Adamo Nagalo, and Mikkel Bro Hansen, who are currently in the infirmary. Ivan Perisic will wear the captain's armband on Thursday, following the absence of Mauro Júnior and Jerdy Schouten, who is already long-term injured with a torn cruciate ligament.