Mourinho's Inter Milan will begin their Champions League campaign away from home, facing a tough test against Real Madrid. The Nerazzurri will be looking to make a strong start to their campaign, but they face a daunting task against one of Europe's top teams. The match will be played at the Santiago Bernabéu, a stadium where Mourinho has enjoyed success in the past.

Inter Milan's Champions League journey will continue with games against Club Brugge (home) and Shakhtar Donetsk (away at Stamford Bridge) on October 13 and October 21, respectively. The match against Liverpool at San Siro is scheduled for January 19, 2027.

Meanwhile, Roma will begin their Champions League campaign away at Fenerbahçe, where they will face their ex-striker Romelu Lukaku and former Lazio star Matteo Guendouzi. In the following round, on October 14, Mourinho will return to the Stadio Olimpico, where Roma will play two consecutive away games in November, visiting Manchester United before facing defending champions PSG.

Napoli will play their opening game against Arsenal at the Stadio Maradona, before visiting Villarreal (October 13) and hosting Bodo/Glimt (October 20). The away game at Manchester City will be played on November 24.