This was a top of the table clash between the only two teams with a perfect record. The Giallorossi had a full squad to choose from, picking summer signings Leonardo Balerdi and Nahuel Molina, with Donyell Malen scoring six goals in four Serie A games. Notably, Wesley was on the right against Federico Dimarco, who was back to full fitness, and Molina the left. Hakan Calhanoglu, John Stones and Djed Spence were injured for Inter.
Inter had gone 2-0 down in their last three competitive games and conceded early again. Molina nodded down the Paulo Dybala cross at the back post, Manu Koné let it bounce and fired in first-time from 10 yards through Manuel Akanji’s legs. The Nerazzurri had tried so hard to buy the France international in recent months, but he struck against them. Roma doubled their lead instead, with Koné turning in at the back post after Gianluca Mancini's flick-on from Dybala's cross.
However, Inter came back to life in the second half, with Lautaro Martinez sweeping in first-time from 12 yards after Marcus Thuram's back-heel flick on a low Carlos Augusto roll across dribbling just wide of the near post. Martinez then nodded the rebound onto the underside of the crossbar before smashing in on the volley from seven yards. Inter eventually battered down the Roma defences to complete yet another comeback from 2-0 down.
The match ended 2-2, with Inter keeping joint top with Roma.