According to Olé, Boca Juniors' defense is still uncertain, with Lautaro Di Lollo's partner in central defense yet to be decided. Facundo Herrera and Marco Pellegrino are the two contenders, but Jagger appears to be in the lead. The youngster was rested for the match against Central Córdoba, while Pellegrino started, a significant sign considering the upcoming match in Brazil. Jagger has also been impressive, playing the full 90 minutes in the first leg against San Pablo.

The midfield situation is also unclear, but three players - Santiago Ascacibar, Paredes, and Alan Velasco - are almost certain to start. Milton Delgado is expected to complete the midfield trio, having recovered from a distension and been out of action since August 28. Coach Arruabarrena had decided to preserve Delgado for the Brazil match, but it remains to be seen if he will start him from the beginning after his inactivity.

In the attack, Miguel Merentiel and Leonel Flores are set to remain the undisputed starters, with the Uruguayan continuing to be the top choice for the Vasco da Gama match. Flores has been impressing, playing alongside Merentiel and edging out Sebastián Villa for a starting spot.