Iraola's comments come as a blow to Liverpool's chances of beating Manchester City, who are set to play their first match since an independent commission found them guilty of breaching Premier League financial rules. The visit of City is the biggest game of Iraola's Liverpool career so far, and despite four wins and three draws, his side have struggled to find their best form.

Iraola expressed his concerns about the duo's fitness, stating that it's now a matter of whether they will recover in time to help the team in the next game or not. The Liverpool head coach also highlighted the importance of his team's defensive improvements, saying that they need to defend against City's threats and also hurt them on the other side.

Liverpool can't afford to be without Isak and Gakpo for their daunting October fixture list, and Iraola will be hoping that the pair can recover in time to face Manchester City.