The team of John van den Brom started the match with a lively display, but failed to capitalize on their early chances. Wout Weghorst had a shot that was just too sharp, while Sondre Ørjasaeter had a scoring opportunity that didn't quite come off. As the first half drew to a close, Qarabag took control, with Jaly Mouaddib having a good chance that was expertly parried by Lars Unnerstall. Kady Borges then brought the ball to safety, but Mouaddib's next action left Bart van Rooij and Marko Pjaca in the lurch. His pass found its way to Borges, who scored the opening goal.

Van den Brom made a tactical switch by introducing Sam Lammers and Kristian Hlynsson, who brought some much-needed energy to the game. Lammers had a few chances, but ultimately it was Qarabag who held on to their lead. The return leg is set to take place next week, with Twente facing a tough task to turn the tie around.